A protein isoform, or " protein variant ", [1] is a member of a set of highly similar proteins that originate from a single gene and are the result of genetic differences. [2] . While many perform …

Protein isoforms/splice variants can play important roles in various biological processes and can potentially be used as biomarkers or therapeutic targets/mediators. Thus, there is a need for …

2018年2月1日 · At its simplest, isoform generation provides a mechanism to specialize the properties of a gene or protein at one of three levels – DNA, messenger RNA (mRNA) or the …

2025年6月9日 · Isoforms play a crucial role in molecular biology, allowing for the diversification of protein function and regulation. They enable cells to respond to different environmental cues, …

2025年4月5日 · A protein isoform is a member of a set of highly similar proteins that originate from a single gene. They are the result of genetic differences and perform the same or similar …

2024年2月8日 · Isozymes, or isoenzymes, are closely related variants of enzymes with identical functions and present in the same individual. They are often coded for by the same organism …

2025年3月26日 · Here, we systematically compared 693 isoforms of 246 TF genes, assessing DNA binding, protein binding, transcriptional activation, subcellular localization, and …

Allozymes, isozymes, and isoforms are three terms that often arise when discussing genetic variation. While they share similarities, each term represents a distinct concept with unique …

In genetics, gene isoforms are mRNAs that are produced from the same locus but are different in their transcription start sites (TSSs), protein coding DNA sequences (CDSs) and/or …

Protein isoforms are originated from the same gene but have distinct amino acid sequences. They are generated by tissue-specific alternative splicing and via alternative transcription start and …