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  1. Metastatic Castration-Resistant Prostate Cancer: Insights on …

    The therapeutic landscape of metastatic hormone sensitive and metastatic castration-resistant prostate cancer (mCRPC) is rapidly changing. We reviewed the current treatment options for …

  2. TRE-5151 Receives FDA Fast Track Designation in …

    The FDA has granted fast track designation to TRE-515 (Trethera Corporation), a novel drug, in combination with radiation therapy for the treatment of prostate cancer. Specifically, the …

  3. FDA Grants Fast Track Designation for TRE-515 in …

    2025年7月10日 · TRE-515 is currently in phase 1 clinical trials for solid tumors. The Fast Track designation applies to TRE-515 in combination with radioligand therapy for the treatment of …

  4. First-in-human results of terbium-161 - The Lancet

    Lutetium-177 (177 Lu)-labelled prostate-specific membrane antigen (PSMA)-targeting radioligand therapy is an established treatment for patients with metastatic castration-resistant prostate …

  5. FDA Approved Pluvicto (177Lu-PSMA-617) for Metastatic …

    Pluvicto gains FDA approval for earlier use in mCRPC. Backed by key trials, it shows improved survival and safety in advanced prostate cancer patients.

  6. The treatment landscape of metastatic castrate-resistant prostate cancer (mCRPC) has been dramatically trans-formed over the past two decades by several leapfrog advances including …

  7. Fast Track Status Granted by FDA to TRE-515 in Prostate Cancer

    2025年7月11日 · The FDA granted fast track designation to TRE-515 plus radioligand therapy for treating PSMA-positive metastatic castration-resistant prostate cancer.

  8. New Drugs for Targeted Radionuclide Therapy in Metastatic Prostate Cancer

    Introduction Metastatic castration-resistant prostate cancer (mCRPC) is an advanced form of prostate cancer and is the second leading cause of cancer-related death among men. …

  9. Landmark Radioligand Therapy Approval Bridges Treatment Gap in mCRPC

    Radiation oncology is an important piece of that, but I also think it’s very important that other physicians across specialties get excited and interested in the radiopharmaceuticals to come. …

  10. Stereotactic Body Radiation Therapy and Abiraterone …

    Treatment options for patients with metastatic castration-resistant prostate cancer (mCRPC) include different systemic agents. Both taxane chemotherapy 1 and androgen …