Factors associated with immunological non-response after ART …
Among people living with HIV (PLHIV) on antiretroviral therapy (ART), the mortality of immunological non-responders (INRs) is higher than that of immunological responders (IRs). …
Why Patients Discontinue ART— and What You Can Do to …
Even with 1-pill ART, patients still discontinue their therapy because of a host of clinical, social, and structural reasons. Clinicians need to educate patients about the dangers of drug holidays …
HIV Antibodies Decline During Antiretroviral Therapy but …
In people with HIV on antiretroviral therapy (ART), the relationship between HIV-specific immune responses and measures of HIV persistence is uncertain. We evaluated 101 individuals on …
HIV treatment failure: Signs to watch - Medical News Today
ART controls a person’s viral load by preventing HIV particles from multiplying. ART can work so well that the virus is undetectable in testing. At this stage, HIV is not transmissible through...
When Undetectable Is Unachievable: Study Offers Insights into HIV ...
New NIAID-funded research suggests that this sometimes can occur when a single cell from the HIV reservoir—the population of long-lived HIV-infected cells that ART cannot …
Immune response to ART initiation in advanced HIV infection
Our objective was to compare the immunological responses to commonly used antiretroviral therapy (ART) regimens among people with advanced HIV in the USA and to assess …
Cellular and molecular insights into incomplete immune recovery in HIV ...
In HIV infection, B cell-mediated immune response is sustained by HIV-specific memory B cells and plasma cells (148). A recent study found that the proportions of naïve B, memory B, and …
Antiretroviral Therapy (ART): How It Works & Side Effects
Antiretroviral therapy (ART) is a combination of medications used to treat HIV (human immunodeficiency virus). It works by stopping HIV from reproducing. It can reduce your levels …
Factors associated with immunological non-response after ART …
We found a sizable immunological non-response rate among HIV-infected patients. Being male, older age, coinfection with HBV and HCV, lower CD4 + T cell count and lower CD4/CD8 ratio …
Immune restoration after antiretroviral therapy: the pitfalls of …
Starting ART may be initially accompanied by aberrant inflammatory responses termed immune reconstitution inflammatory syndrome (IRIS), wherein patients experience paradoxical …