Abstract The generation of hematopoietic stem cells (HSCs) from induced pluripotent stem cells (iPSCs) is an active and promising area of research; however, generating engraftable HSCs …

The definition of hematopoietic stem cell has developed since they were first discovered in 1961. [6] The hematopoietic tissue contains cells with long-term and short-term regeneration …

Hematopoiesis from Pluripotent Stem Cells Hematopoietic stem cells (HSCs) have the property of self-renewal and,, through cell division and differentiation, form populations of progenitor cells …

Establishment of pluripotent stem cells provides a comprehensive model to study early hematopoietic development and has emerged as a powerful research tool to explore …

Induced pluripotent stem cells (iPSCs) are generated by reprogramming adult cells, typically skin fibroblasts or blood cells, to a pluripotent state. This reprogramming is achieved by introducing …