So how do drug molecules (and others) get into cells, anyway? There are two broad answers: they just sort of slide in through the membranes on their own (passive diffusion), or they're …

Drug transporters are integral membrane proteins that play a critical role in drug disposition by affecting absorption, distribution, and excretion. They translocate drugs, as well as …

There are several ways to gain entry into the cell, if your receptor happens to be intracellular. - Grab the drug from the extracellular fluid and actively transport the drug into the cell. How fast …

Plasma membrane acts as an important biological barrier for the movement of drugs. Movements of drugs occur by simple diffusion, filtration, facilitated diffusion, active transport, endocytosis, …

Drug passage across the cell membrane branes to reach their site of action. A common feature of all cell membranes is a phospholipid bilayer, about 10 nm thick, arranged with the hydrophilic …

Absorption is the entry of the drug molecules into the blood via the mucous membranes of the alimentary or respiratory tracts or from the site of injection. Distribution is the movement of the …

The processes of diffusion, osmosis, and filtration are responsible for the movement of materials into and out of body cells as well as the exchange of molecules between body fluid …

1. Splanchnic circulation – which is the network of blood vessels that supply the GIT. It is the major route for absorption of drug into the systemic circulation. A drug that enters splanchnic …

Excretion is the process through which drugs and their metabolites are eliminated from the body. The kidneys play a dominant role, filtering blood and excreting waste through urine. Renal …

Paracellular and transmembrane diffusion takes forever, and few drugs have access to a handy active transporter. The body is made of cells, they are enveloped in lipid, and this lipid …