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  1. Imetelstat was approved by the United States Food and Drug Administration in June 2024 and the European Medicines Agency in March 2025 for the treatment of certain patients with lower-risk …

  2. Updated NCCN Guidelines Recommend Imetelstat to Treat Anemia

    Imetelstat is an liquidated oligonucleotide telomerase inhibitor approved for treating adult patients with low-to-intermediate-1 risk MDS with transfusion-dependent anemia.1 The first-in-class …

  3. Updated NCCN Guidelines Recommend Imetelstat for Anemia

    The National Comprehensive Cancer Network (NCCN) has updated its Clinical Practice Guidelines in Oncology to recommend imetelstat (Rytelo) as a Category 1 and 2A treatment …

  4. Why RYTELO (imetelstat) | RYTELOHCP

    RYTELO® (imetelstat) is indicated for the treatment of adult patients with low- to intermediate-1 risk myelodysplastic syndromes (MDS) with transfusion-dependent anemia requiring 4 or more …

  5. Imetelstat (Rytelo): a promising treatment for adults with …

    These molecular discoveries underscore Imetelstat’s capacity to impact the course of MDS, setting it apart from other treatments that chiefly target anemia-related symptoms. When …

  6. FDA approves imetelstat for low- to intermediate-1 risk …

    Drug Approvals and Databases Resources for Information | Approved Drugs FDA approves imetelstat for low- to intermediate-1 risk myelodysplastic syndromes with transfusion …

  7. Institute for Clinical and Economic Review Publishes …

    ICER posted its revised Evidence Report assessing the comparative clinical effectiveness and value of imetelstat (Rytelo, Geron Corporation) for the treatment of anemia in myelodysplastic …

  8. Imetelstat: a new addition to the therapeutic landscape of …

    Anemia is the most prevalent cytopenia in lower-risk myelodysplastic neoplasms (LR-MDS). There is a paucity of drugs for red blood cell transfusion dependence (RBC-TD), and …

  9. Evaluating Imetelstat's Impact on Health-Related Quality of …

    3 天之前 · The phase 3 IMerge trial (NCT02598661) evaluated how treatment with imetelstat impacts health-related quality of life in patients with lower-risk myelodysplastic syndromes …

  10. Updated NCCN Guidelines Recommend Imetelstat for Symptomatic Anemia

    On July 26, Geron Corporation announced that the National Comprehensive Cancer Network (NCCN) has updated its Clinical Practice Guidelines in Oncology (NCCN Guidelines) for the …

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