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生物通
19 天
肺腺癌中与间充质干细胞增殖分化相关的生物标志物 ...
编辑推荐: 本研究针对肺腺癌 (LUAD)中间充质干细胞 (MSCs)调控机制不明的问题,通过整合TCGA和GEO多组学数据,首次鉴定出MS4A2、IGSF10、NTRK3和MFAP3L四个关键生物标志物。研究构建的预后风险模型能有效预测患者生存,并揭示这些标志物通过调控间质-上皮转化 (MET)和肿瘤微环境重塑影响疾病进展,为 ...
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