BACKGROUND: Direct reprogramming of fibroblasts to cardiomyocytes is a potentially curative strategy for ischemic heart ...

One promising strategy to remuscularize the injured heart is the direct cardiac reprogramming of heart fibroblast cells into cardiomyocytes. Researchers have identified TBX20 as the key missing ...

SeamlessTx is addressing this challenge with a unique platform that integrates large-scale directed evolution and machine learning (ML)-driven models to predict recombinase variant activity and ...

A new way of reprogramming our immune cells to shrink or kill off cancer cells has been shown to work in the otherwise hard to treat and devastating skin cancer, melanoma. The discovery ...

Hao Huang from Mass's lab. "And this happened even when the young animals were fed a completely normal diet." The cause of this disorder seems to be a kind of "reprogramming" of the Kupffer cells in ...

In a study published in the prestigious journal Nature Cancer, researchers led by Professor Cédric Blanpain, MD/PhD, WELBIO researcher, director of the Stem Cells and Cancer Laboratory, and professor ...

Emerging contaminants (ECs), including pharmaceuticals, microplastics, per- and polyfluoroalkyl substances (PFAS), antibiotic ...

The mice were already 124 weeks old at the time, so this only represents a 7 percent increase in lifespan. But the company says it's still a significant demonstration of the potential life-extending ...

At ISSCR Lonza recently introduced its new L7™ hiPSC Reprogramming and hPSC Culture System for basic stem-cell research, disease modeling, drug development and regenerative medicine. The L7™ System ...

Knocking out a single gene reprograms part of the large intestine to function like the nutrient-absorbing small intestine. In a preclinical study, Weill Cornell Medicine investigators showed that the ...