BACKGROUND: Direct reprogramming of fibroblasts to cardiomyocytes is a potentially curative strategy for ischemic heart ...

SeamlessTx is addressing this challenge with a unique platform that integrates large-scale directed evolution and machine learning (ML)-driven models to predict recombinase variant activity and ...

Hao Huang from Mass's lab. "And this happened even when the young animals were fed a completely normal diet." The cause of this disorder seems to be a kind of "reprogramming" of the Kupffer cells in ...

A new way of reprogramming our immune cells to shrink or kill off cancer cells has been shown to work in the otherwise hard to treat and devastating skin cancer, melanoma. The discovery ...

One promising strategy to remuscularize the injured heart is the direct cardiac reprogramming of heart fibroblast cells into cardiomyocytes. Researchers have identified TBX20 as the key missing ...

Prostate cancer is one of the most common cancers and the second leading cause of cancer-related death in men worldwide. However, the mechanisms controlling the early stages of prostate cancer ...

Knocking out a single gene reprograms part of the large intestine to function like the nutrient-absorbing small intestine. In a preclinical study, Weill Cornell Medicine investigators showed that the ...

Emerging contaminants (ECs), including pharmaceuticals, microplastics, per- and polyfluoroalkyl substances (PFAS), antibiotic ...

At ISSCR Lonza recently introduced its new L7™ hiPSC Reprogramming and hPSC Culture System for basic stem-cell research, disease modeling, drug development and regenerative medicine. The L7™ System ...

Billions of dollars are pouring into longevity startups as a growing body of research shows that aging might not be as inevitable as we assumed. Now, a startup claims to have reached a major milestone ...

Heart tissue normally can't regenerate after an injury. But now, scientists at Max Planck have shown in mice that reprogramming the energy metabolism of the heart allows it to regenerate after a ...