Intraductal neoplasms of the bile duct are macroscopically characterized by exophytic or polypoid growth patterns and have a favorable prognosis. Although some tumors with a predominantly tubular ...

Bile duct cancer cells and normal cells 3D photolithography image difference Bile duct cancer, a malignant tumor that occurs in the bile duct, is difficult to diagnose early because there are few ...

在肝内胆管癌（ICC）治疗领域，化疗免疫治疗（CIT）取得了显著进展，但仍面临着治疗抵抗的挑战。铁死亡是一种细胞死亡形式，与癌症的发生、发展及治疗抵抗密切相关。PCK1作为代谢关键酶，在多种癌症中发挥着重要作用，但其在ICC中的具体作用尚不清楚。

肝内胆管癌(intrahepatic cholangiocarcinoma, iCCA)的预后不佳，很大原因是由于诊断不够及时造成的，因此iCCA的早期诊断和及早治疗是提高疾病治愈效果的 ...

The aim of this study was to identify the pattern and significance of expression of p53 and PCNA in cholangiocarcinoma and primary sclerosing cholangitis. Histological sections from 18 patients ...

Cholangiocarcinoma, also known as bile duct cancer, is a rare disease. It's a devasting condition incurable at the point ...

Chemoradiation combined with immunotherapy significantly boosts survival in patients with resected extrahepatic ...

In a follow-up analysis to the pivotal TOPAZ-1 study, which established the combination therapy of durvalumab (an ...

Intrahepatic cholangiocarcinoma (IHCCA), a global health problem, is increasing in incidence and has differing etiologies worldwide. Next-generation sequencing (NGS) is rapidly being incorporated into ...

Cholangiocarcinoma is a relatively rare adenocarcinoma of the bile ducts that is rapidly fatal unless it can be completely resected. In most cases, the tumor is too advanced for resection by the ...

Across the 3 cholangiocarcinoma subtypes, OS of more than 3 years was associated with lower percentages of PD-1+ cells among the CD8+ T cells than those with OS of less than 3 years.

The “ubiquitous dependency” of cholangiocarcinoma on CDK4/6 activity, Kongpetch said, suggests that the that the CDK4/6-pRB pathway could be a treatable target.